SPLUNC1 Regulates Cell Progression and Apoptosis through the miR-141-PTEN/p27 Pathway, but Is Hindered by LMP1

Little is known about the role of the host defensive protein short palate, lung and nasal epithelium clone 1 (SPLUNC1) in the carcinogenesis of nasopharyngeal carcinoma (NPC). Here we report that SPLUNC1 plays a role at a very early stage of NPC carcinogenesis. SPLUNC1 regulates NPC cell proliferati...

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Detalhes bibliográficos
Main Authors: Chen, Pan, Guo, Xiaofang, Zhou, Houde, Zhang, Wenling, Zeng, Zhaoyang, Liao, Qianjin, Li, Xiayu, Xiang, Bo, Yang, Jianbo, Ma, Jian, Zhou, Ming, Peng, Shuping, Xiang, Juanjuan, Li, Xiaoling, LE, Colvin Wanshura, Xiong, Wei, McCarthy, James B., Li, Guiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589440/
https://ncbi.nlm.nih.gov/pubmed/23472073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056929
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