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Tom70 Is Essential for PINK1 Import into Mitochondria

PTEN induced kinase 1 (PINK1) is a serine/threonine kinase in the outer membrane of mitochondria (OMM), and known as a responsible gene of Parkinson's disease (PD). The precursor of PINK1 is synthesized in the cytosol and then imported into the mitochondria via the translocase of the OMM (TOM)...

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Detalhes bibliográficos
Main Authors: Kato, Hiroki, Lu, Qiping, Rapaport, Doron, Kozjak-Pavlovic, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589387/
https://ncbi.nlm.nih.gov/pubmed/23472196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058435
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