Clonal Expansions of CD8(+) T Cells with IL-10 Secreting Capacity Occur during Chronic Mycobacterium tuberculosis Infection

The exact role of CD8(+) T cells during Mycobacterium tuberculosis (Mtb) infection has been heavily debated, yet it is generally accepted that CD8(+) T cells contribute to protection against Mtb. In this study, however, we show that the Mtb-susceptible CBA/J mouse strain accumulates large numbers of...

Full description

Saved in:
Bibliographic Details
Main Authors: Cyktor, Joshua C., Carruthers, Bridget, Beamer, Gillian L., Turner, Joanne
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589362/
https://ncbi.nlm.nih.gov/pubmed/23472214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058612
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items