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Successful TRPV1 antagonist treatment for cardiac hypertrophy and heart failure in mice

Heart failure is becoming a global epidemic. It exerts a staggering toll on quality of life, and substantial medical and economic impact. In a pre-clinical model of cardiac hypertrophy and heart failure, we were able to overcome loss of heart function by administering the TRPV1 antagonist BCTC (4-(3...

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Detalhes bibliográficos
Main Authors: Horton, Jaime S., Buckley, Cadie L., Stokes, Alexander J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589277/
https://ncbi.nlm.nih.gov/pubmed/23221478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.23006
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