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The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway

The INhibitor of Growth (ING) proteins act as type II tumor suppressors and epigenetic regulators, being stoichiometric members of histone acetyltransferase and histone deacetylase complexes. Expression of the alternatively spliced ING1a tumor suppressor increases >10-fold during replicative sene...

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Bibliografski detalji
Glavni autori: Rajarajacholan, Uma Karthika, Thalappilly, Subhash, Riabowol, Karl
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589274/
https://ncbi.nlm.nih.gov/pubmed/23472054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001502
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