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Hepatocyte-specific expression of the hepatitis B virus core promoter depends on both positive and negative regulation.

The core promoter of hepatitis B virus shows hepatocyte specificity, which is largely dependent on an upstream regulatory sequence that overlaps with viral enhancer II. Footprint analyses by numerous groups have shown binding by cellular proteins over a large stretch of DNA in this region, but the i...

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Autors principals: Guo, W, Chen, M, Yen, T S, Ou, J H
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC358924/
https://ncbi.nlm.nih.gov/pubmed/8417343
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