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Therapeutic Assessment of Cytochrome C for the Prevention of Obesity Through Endothelial Cell-targeted Nanoparticulate System
Because the functional apoptosis-initiating protein, cytochrome C (CytC) is rapidly cleared from the circulation (t(1/2) (half-life): 4 minutes), it cannot be used for in vivo therapy. We report herein on a hitherto unreported strategy for delivering exogenous CytC as a potential and safe antiobesit...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589155/ https://ncbi.nlm.nih.gov/pubmed/23295953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.256 |
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