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Impact of Endothelin A Receptor Antagonist Selectivity in Chronic Nitric Oxide Synthase Inhibition-Induced Fetal Growth Restriction in the Rat

OBJECTIVE: Endothelin receptor A (ET(A)) antagonism improves fetal and placental growth and placental perfusion on days 1 and 4, but not day 7 of a 7-day infusion of a nitric oxide synthase (NOS) inhibitor. Our purpose was to evaluate the significance of the degree of ET(A) antagonist selectivity on...

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Bibliografische gegevens
Hoofdauteurs: Neerhof, Mark G., Synowiec, Sylvia, Khan, Saira, Thaete, Larry G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589146/
https://ncbi.nlm.nih.gov/pubmed/20504166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10641950902777739
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