Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo

Monocyte chemoattractant protein-1 (MCP-1)-induced monocyte chemotaxis is a major event in inflammatory disease. Our prior studies have demonstrated that MCP-1-dependent chemotaxis requires release of arachidonic acid (AA) by activated cytosolic phospholipase A(2) (cPLA(2)). Here we investigated the...

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Autori principali: Kundu, Suman, Roome, Talat, Bhattacharjee, Ashish, Carnevale, Kevin A., Yakubenko, Valentin P., Zhang, Renliang, Hwang, Sung Hee, Hammock, Bruce D., Cathcart, Martha K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588870/
https://ncbi.nlm.nih.gov/pubmed/23160182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M031914
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