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Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging.

Human diploid fibroblasts undergo a limited number of population doublings in vitro and are used widely as a model of cellular aging. Despite growing evidence that cellular aging occurs as a consequence of altered gene expression, little is known about the activity of transcription factors in aging...

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Bibliografiska uppgifter
Huvudupphovsmän: Atadja, P W, Stringer, K F, Riabowol, K T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC358870/
https://ncbi.nlm.nih.gov/pubmed/8007992
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