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A Human Genome-wide Screen for Regulators of Clathrin-coated Vesicle Formation Reveals an Unexpected Role for the V-ATPase
Clathrin-mediated endocytosis is essential for a wide range of cellular functions. We used a multi-step siRNA-based screening strategy to identify regulators of the first step in clathrin-mediated endocytosis, formation of clathrin-coated vesicles (CCVs) at the plasma membrane. A primary genome-wide...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3588604/ https://ncbi.nlm.nih.gov/pubmed/23263279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2652 |
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