Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation.

Erythropoietin (EPO) is a prime regulator of the growth and differentiation of erythroid blood cells. The EPO receptor (EPO-R) is expressed in late erythroid progenitors (mature BFU-E and CFU-E), and EPO induces proliferation and differentiation of these cells. By introducing, with a retroviral vect...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Dubart, A, Feger, F, Lacout, C, Goncalves, F, Vainchenker, W, Dumenil, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8007982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.7.4834-4842.1994
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