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Enhancement of Cisplatin-Mediated Apoptosis in Ovarian Cancer Cells through Potentiating G2/M Arrest and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane

Advanced-stage ovarian cancer is characterized by high mortality due to development of resistance to conventional chemotherapy. Novel compounds that can enhance the efficacy of conventional chemotherapy in ovarian cancer may overcome this drug resistance. Consumption of green tea (epigallocatechin g...

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Autors principals: Chen, Huaping, Landen, Charles N., Li, Yuanyuan, Alvarez, Ronald D., Tollefsbol, Trygve O.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588178/
https://ncbi.nlm.nih.gov/pubmed/23476648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/872957
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