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Evidence for the Involvement of RhoA Signaling in the Ethanol-Induced Increase in Intestinal Epithelial Barrier Permeability

In this work, we investigated the potential role of the small G protein RhoA in ethanol-induced tight junction (TJ) protein disassembly and increased intestinal epithelial barrier (IEB) permeability. Our study used Caco-2 cells as an in vitro IEB model and RhoA short hairpin RNA (shRNA) interference...

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Autori principali: Tong, Jing, Wang, Ying, Chang, Bing, Zhang, Dai, Wang, Bingyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588079/
https://ncbi.nlm.nih.gov/pubmed/23429187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14023946
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