Analysis of the Enhanced Stability of R(+)-Alpha Lipoic Acid by the Complex Formation with Cyclodextrins

R(+)-alpha lipoic acid (RALA) is one of the cofactors for mitochondrial enzymes and, therefore, plays a central role in energy metabolism. RALA is unstable when exposed to low pH or heat, and therefore, it is difficult to use enantiopure RALA as a pharma- and nutra-ceutical. In this study, we have a...

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Main Authors: Ikuta, Naoko, Sugiyama, Hironori, Shimosegawa, Hiroshi, Nakane, Rie, Ishida, Yoshiyuki, Uekaji, Yukiko, Nakata, Daisuke, Pallauf, Kathrin, Rimbach, Gerald, Terao, Keiji, Matsugo, Seiichi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588062/
https://ncbi.nlm.nih.gov/pubmed/23434662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14023639
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