JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region.

The high-affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF) consists of a unique alpha chain and a beta c subunit that is shared with the receptors for interleukin-3 (IL-3) and IL-5. Two regions of the beta c chain have been defined; these include a membrane-proximal reg...

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Bibliografische gegevens
Hoofdauteurs: Quelle, F W, Sato, N, Witthuhn, B A, Inhorn, R C, Eder, M, Miyajima, A, Griffin, J D, Ihle, J N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC358804/
https://ncbi.nlm.nih.gov/pubmed/8007942
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