Compound K, a Ginsenoside Metabolite, Inhibits Colon Cancer Growth via Multiple Pathways Including p53-p21 Interactions

Compound K (20-O-beta-d-glucopyranosyl-20(S)-protopanaxadiol, CK), an intestinal bacterial metabolite of ginseng protopanaxadiol saponins, has been shown to inhibit cell growth in a variety of cancers. However, the mechanisms are not completely understood, especially in colorectal cancer (CRC). A xe...

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Autori principali: Zhang, Zhiyu, Du, Guang-Jian, Wang, Chong-Zhi, Wen, Xiao-Dong, Calway, Tyler, Li, Zejuan, He, Tong-Chuan, Du, Wei, Bissonnette, Marc, Musch, Mark W., Chang, Eugene B., Yuan, Chun-Su
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588026/
https://ncbi.nlm.nih.gov/pubmed/23434653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14022980
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