Measurement of the Interaction Between Recombinant I-domain from Integrin alpha 2 beta 1 and a Triple Helical Collagen Peptide with the GFOGER Binding Motif Using Molecular Force Spectroscopy

The role of the collagen-platelet interaction is of crucial importance to the haemostatic response during both injury and pathogenesis of the blood vessel wall. Of particular interest is the high affinity interaction of the platelet transmembrane receptor, alpha 2 beta 1, responsible for firm attach...

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Main Authors: Attwood, Simon J., Simpson, Anna M. C., Hamaia, SamirW., Bihan, Dominique, Roy, Debdulal, Farndale, RichardW., Welland, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588017/
https://ncbi.nlm.nih.gov/pubmed/23434650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14022832
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