Post-transcriptional regulation of IGF1R by key microRNAs in long-lived mutant mice

Long-lived mutant mice, both Ames dwarf and growth hormone receptor gene disrupted or knockout (GHRKO) strains, exhibit heightened cognitive robustness and altered IGF1 signaling in the brain. Here we report, in both these long-lived mice, that three up-regulated lead microRNAs, miR-470, −669b, and...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Liang, Ruqiang, Khanna, Amit, Muthusamy, Senthilkumar, Li, Na, Sarojini, Harshini, Kopchick, John J., Masternak, Michal M., Bartke, Andrzej, Wang, Eugenia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587961/
https://ncbi.nlm.nih.gov/pubmed/21967153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00751.x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky