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Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle.

The proto-oncogene transcription factors Fos and Jun form a heterodimeric complex that binds to DNA and regulates expression of specific target genes. Continuous expression of c-fos causes transformation of cultured fibroblasts and induces osteogenic sarcoma in mice. To investigate the molecular bas...

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Detalhes bibliográficos
Main Authors: Miao, G G, Curran, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC358796/
https://ncbi.nlm.nih.gov/pubmed/8196666
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