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Glibenclamide enhances neurogenesis and improves long-term functional recovery after transient focal cerebral ischemia

Glibenclamide is neuroprotective against cerebral ischemia in rats. We studied whether glibenclamide enhances long-term brain repair and improves behavioral recovery after stroke. Adult male Wistar rats were subjected to transient middle cerebral artery occlusion (MCAO) for 90 minutes. A low dose of...

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Détails bibliographiques
Auteurs principaux: Ortega, Francisco J, Jolkkonen, Jukka, Mahy, Nicole, Rodríguez, Manuel J
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587805/
https://ncbi.nlm.nih.gov/pubmed/23149556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.166
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