Bortezomib Reduces the Tumorigenicity of Multiple Myeloma via Downregulation of Upregulated Targets in Clonogenic Side Population Cells

Side population (SP) cells in cancers, including multiple myeloma, exhibit tumor-initiating characteristics. In the present study, we isolated SP cells from human myeloma cell lines and primary tumors to detect potential therapeutic targets specifically expressed in SP cells. We found that SP cells...

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Detalhes bibliográficos
Main Authors: Nara, Miho, Teshima, Kazuaki, Watanabe, Atsushi, Ito, Mitsugu, Iwamoto, Keiko, Kitabayashi, Atsushi, Kume, Masaaki, Hatano, Yoshiaki, Takahashi, Naoto, Iida, Shinsuke, Sawada, Kenichi, Tagawa, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587640/
https://ncbi.nlm.nih.gov/pubmed/23469177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056954
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