Fine-Mapping Angiotensin-Converting Enzyme Gene: Separate QTLs Identified for Hypertension and for ACE Activity

Angiotensin-converting enzyme (ACE) has been implicated in multiple biological system, particularly cardiovascular diseases. However, findings associating ACE insertion/deletion polymorphism with hypertension or other related traits are inconsistent. Therefore, in a two-stage approach, we aimed to f...

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Detalhes bibliográficos
Main Authors: Chung, Chia-Min, Wang, Ruey-Yun, Fann, Cathy S. J., Chen, Jaw-Wen, Jong, Yuh-Shiun, Jou, Yuh-Shan, Yang, Hsin-Chou, Kang, Chih-Sen, Chen, Chien-Chung, Chang, Huan-Cheng, Pan, Wen-Harn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587614/
https://ncbi.nlm.nih.gov/pubmed/23469169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056119
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