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Effectiveness of the Histone Deacetylase Inhibitor (S)-2 against LNCaP and PC3 Human Prostate Cancer Cells

Histone deacetylase inhibitors (HDACi) represent a promising class of epigenetic agents with anticancer properties. Here, we report that (S)-2, a novel hydroxamate-based HDACi, shown previously to be effective against acute myeloid leukemia cells, was also a potent inducer of apoptosis/differentiati...

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Bibliografiska uppgifter
Huvudupphovsmän: Laurenzana, Anna, Balliu, Manjola, Cellai, Cristina, Romanelli, Maria Novella, Paoletti, Francesco
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587597/
https://ncbi.nlm.nih.gov/pubmed/23469273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058267
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