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Impaired Acetylcholine-Induced Endothelium-Dependent Aortic Relaxation by Caveolin-1 in Angiotensin II-Infused Apolipoprotein-E (ApoE(−/−)) Knockout Mice

OBJECTIVE: The angiotensin II (AngII)-infused apolipoprotein E-deficient (ApoE(−/−)) mouse model is widely used to study atherosclerosis and abdominal aortic aneurysm. An increase in blood pressure has been reported in this model however the underlying mechanism has not been fully explored. In this...

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Detalhes bibliográficos
Main Authors: Seto, Sai Wang, Krishna, Smriti M., Yu, Hongyou, Liu, David, Khosla, Surabhi, Golledge, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587590/
https://ncbi.nlm.nih.gov/pubmed/23469284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058481
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