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Mosaic Trisomy 21 and Trisomy 14 as Acquired Cytogenetic Abnormalities without GATA1 Mutation in A Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia

One case of acute megakaryoblastic leukemia (AMKL) with trisomy 21, trisomy 14 and unmutated GATA1 gene in a phenotypically normal girl was reported. The patient experienced transient myelodysplasia before the onset of AMKL. The bone marrow blasts manifested typical morphology of megakaryoblast both...

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Detalhes bibliográficos
Main Authors: Xiao, Yi, Wei, Jia, Xu, Jin-huan, Zhou, Jian-feng, Zhang, Yi-cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag Berlin Heidelberg 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587565/
https://ncbi.nlm.nih.gov/pubmed/23467713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11670-011-0239-4
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