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Eukaryotic GPN-loop GTPases paralogs use a dimeric assembly reminiscent of archeal GPN

GTPases are molecular switches that regulate a wide-range of cellular processes. The GPN-loop GTPase (GPN) is a sub-family of P-loop NTPase that evolved from a single gene copy in archaea to triplicate paralog genes in eukaryotes, each having a non-redundant essential function in cell. In Saccharomy...

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Detalhes bibliográficos
Main Authors: Alonso, Béatrice, Beraud, Carole, Meguellati, Sarra, Chen, Shu W., Pellequer, Jean Luc, Armengaud, Jean, Godon, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587447/
https://ncbi.nlm.nih.gov/pubmed/23324351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23367
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