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Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex

The molecular structure of the yeast nuclear pore complex (NPC) and the translocation of model particles have been studied with a molecular theory that accounts for the geometry of the pore and the sequence and anchoring position of the unfolded domains of the nucleoporin proteins (the FG-Nups), whi...

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Detalhes bibliográficos
Main Authors: Tagliazucchi, Mario, Peleg, Orit, Kröger, Martin, Rabin, Yitzhak, Szleifer, Igal
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587244/
https://ncbi.nlm.nih.gov/pubmed/23404701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212909110
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