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Small molecule inhibitor of lipoteichoic acid synthesis is an antibiotic for Gram-positive bacteria

The current epidemic of infections caused by antibiotic-resistant Gram-positive bacteria requires the discovery of new drug targets and the development of new therapeutics. Lipoteichoic acid (LTA), a cell wall polymer of Gram-positive bacteria, consists of 1,3-polyglycerol-phosphate linked to glycol...

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Detalhes bibliográficos
Main Authors: Richter, Stefan G., Elli, Derek, Kim, Hwan Keun, Hendrickx, Antoni P. A., Sorg, Joseph A., Schneewind, Olaf, Missiakas, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587227/
https://ncbi.nlm.nih.gov/pubmed/23401520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217337110
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