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Male-specific lethal complex in Drosophila counteracts histone acetylation and does not mediate dosage compensation

Dosage compensation is achieved in male Drosophila by a twofold up-regulation of the single X chromosome to reach the level of the two X chromosomes in females. A popular hypothesis to explain this phenomenon is that the male-specific lethal (MSL) complex, which is present at high levels on the male...

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Detalhes bibliográficos
Main Authors: Sun, Lin, Fernandez, Harvey R., Donohue, Ryan C., Li, Jilong, Cheng, Jianlin, Birchler, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587201/
https://ncbi.nlm.nih.gov/pubmed/23382189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222542110
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