A cis-acting element in retroviral genomic RNA links Gag-Pol ribosomal frameshifting to selective viral RNA encapsidation

During retroviral RNA encapsidation two full length genomic (g) RNAs are selectively incorporated into assembling virions. Packaging involves a cis-acting packaging element (ψ) within the 5'-untranslated region of unspliced HIV-1 RNA genome. However, the mechanism(s) that selects and limits gRN...

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Main Authors: Chamanian, Mastooreh, Purzycka, Katarzyna J., Wille, Paul T., Ha, Janice S., McDonald, David, Gao, Yong, Le Grice, Stuart F.J., Arts, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587049/
https://ncbi.nlm.nih.gov/pubmed/23414758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.01.007
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