Familial Defective Apolipoprotein B-100 and Increased Low-Density Lipoprotein Cholesterol and Coronary Artery Calcification in the Old Order Amish

BACKGROUND: Elevated low-density lipoprotein cholesterol (LDL-C) levels are a major cardiovascular disease risk factor. Genetic factors are an important determinant of LDL-C levels. METHODS: To identify single nucleotide polymorphisms associated with LDL-C and subclinical coronary atherosclerosis, w...

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Autori principali: Shen, Haiqing, Damcott, Coleen M., Rampersaud, Evadnie, Pollin, Toni I., Horenstein, Richard B., McArdle, Patrick F., Peyser, Patricia A., Bielak, Lawrence F., Post, Wendy S., Chang, Yen-Pei C., Ryan, Kathleen A., Miller, Michael, Rumberger, John A., Sheedy, Patrick F., Shelton, John, O’Connell, Jeffrey R., Shuldiner, Alan R., Mitchell, Braxton D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587042/
https://ncbi.nlm.nih.gov/pubmed/21059979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archinternmed.2010.384
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