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Radiation-induced Galectin-1 by endothelial cells: A promising molecular target for preferential drug delivery to the tumor vasculature

The present study reports on a new strategy for selective, radiation therapy-amplified drug delivery using an antiangiogenic 33-a.a., tumor vasculature targeting ligand, anginex to improve the therapeutic ratio for strategies developed against solid tumors. Our findings indicate that Galectin-1 is (...

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Détails bibliographiques
Auteurs principaux: Upreti, Meenakshi, Jamshidi-Parsian, Azemat, Apana, Scott, Berridge, Marc, Fologea, Daniel A, Koonce, Nathan A, Henry, Ralph L, Griffin, Robert J
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586987/
https://ncbi.nlm.nih.gov/pubmed/23090010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0965-1
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