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Decreased CD5(+) B Cells in Active ANCA Vasculitis and Relapse after Rituximab

BACKGROUND AND OBJECTIVES: B cell significance in ANCA disease pathogenesis is underscored by the finding that ANCA alone can cause disease in mouse models and by the effectiveness of rituximab as therapy in ANCA-small vessel vasculitis (ANCA-SVV). To avoid infections and adverse events from therapy...

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Autori principali: Bunch, Donna O’Dell, McGregor, JulieAnne G., Khandoobhai, Nirmal B., Aybar, Lydia T., Burkart, Madelyn E., Hu, Yichun, Hogan, Susan L., Poulton, Caroline J., Berg, Elisabeth A., Falk, Ronald J., Nachman, Patrick H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586963/
https://ncbi.nlm.nih.gov/pubmed/23293123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.03950412
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