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Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines.

Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor which binds to decameric DNA sequences (kappa B sites) and regulates transcription of multiple genes. The activity of NF-kappa B is regulated by an inhibitor protein, I kappa B, which sequesters NF-kappa B in the cytoplasm. Rel...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Miyamoto, S, Chiao, P J, Verma, I M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8164680/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.5.3276
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