Different Expression of Extracellular Signal-Regulated Kinases (ERK) 1/2 and Phospho-Erk Proteins in MBA-MB-231 and MCF-7 Cells after Chemotherapy with Doxorubicin or Docetaxel

OBJECTIVE(S): Curative treatment of breast cancer patients using chemotherapy often fails as a result of intrinsic or acquired resistance of the tumor to the drug. ERK is one of the main components of the Ras/Raf/MEK/ERK cascade, which mediates signal from cell surface receptors to transcription fac...

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Bibliographic Details
Main Authors: Taherian, Aliakbar, Mazoochi, Tahereh
Format: Artigo
Language:Inglês
Published: Mashhad University of Medical Sciences 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586869/
https://ncbi.nlm.nih.gov/pubmed/23493035
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