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Where PI3K/Akt Meets Smads: the Crosstalk Determines Human Embryonic Stem Cell Fate
Coordinated interactions between signaling networks govern the balance of cell fate decisions in human embryonic stem cells. In this issue, Singh et al. (2012) report that PI3K/Akt signaling switches Activin/Smad activity between pro-self-renewal and pro-differentiation by regulating ERK and GSK3β/β...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586792/ https://ncbi.nlm.nih.gov/pubmed/22385648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.02.008 |
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