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Structural and Physicochemical Aspects of Dasatinib Hydrate and Anhydrate phases

Crystal structures for the commercial monohydrate form and an anhydrate form of dasatinib, an oral anti-cancer agent, are presented along with characterization by Raman spectroscopy, powder X-ray diffraction, differential scanning calorimetry, and thermogravimetric analysis. Solubility measurements...

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Detalhes bibliográficos
Main Authors: Roy, Saikat, Quiñones, Rosalynn, Matzger, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586737/
https://ncbi.nlm.nih.gov/pubmed/23472049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cg300152p
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