DNA-binding-defective mutants of the Epstein-Barr virus lytic switch activator Zta transactivate with altered specificities.

The Epstein-Barr virus BRLF1 and BZLF1 genes are the first viral genes transcribed upon induction of the viral lytic cycle. The protein products of both genes (referred to here as Rta and Zta, respectively) activate expression of other viral genes, thereby initiating the lytic cascade. Among the vir...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Flemington, E K, Lytle, J P, Cayrol, C, Borras, A M, Speck, S H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8164660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.5.3041-3052.1994
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