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IGF-1 promotes the development and cytotoxic activity of human NK cells

Insulin-like growth factor 1 (IGF-1) is a critical regulator of many physiological functions, ranging from longevity to immunity. However, little is known about the role of IGF-1 in natural killer cell development and function. Here, we identify an essential role for IGF-1 in the positive regulation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ni, Fang, Sun, Rui, Fu, Binqing, Wang, Fuyan, Guo, Chuang, Tian, Zhigang, Wei, Haiming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586714/
https://ncbi.nlm.nih.gov/pubmed/23403580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2484
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