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Kupffer Cells Protect Liver Sinusoidal Endothelial Cells from Fas-Dependent Apoptosis in Sepsis by Down-Regulating gp130

Endothelial cell (EC) dysfunction is a key feature of multiple organ injury, the primary cause of fatality seen in critically ill patients. Although the development of EC dysfunction in the heart and lung is well studied in sepsis, it remains unclear in the liver. Herein, we report that liver sinuso...

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Hlavní autoři: Hutchins, Noelle A., Chung, Chun-Shiang, Borgerding, Joshua N., Ayala, Carol A., Ayala, Alfred
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586691/
https://ncbi.nlm.nih.gov/pubmed/23306157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.11.023
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