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Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly.

Highly purified mammalian spliceosomal complex B contains more than 30 specific protein components. We have carried out UV cross-linking studies to determine which of these components directly contacts pre-mRNA in purified prespliceosomal and spliceosomal complexes. We show that heterogeneous nuclea...

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Publicat a:Mol Cell Biol
Autors principals: Staknis, D, Reed, R
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358667/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8164655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.5.2994-3005.1994
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