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Biomarkers for EGFR-Antagonist Response: In the Genes and on the Genes!

Patients with non–small cell lung carcinoma containing epidermal growth factor receptor (EGFR)–activating mutations benefit from EGFR-antagonist therapy. EGFR-antagonist sensitivity is also correlated with epithelial–mesenchymal transition, which Walter and colleagues show to be marked by DNA-methyl...

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Detalhes bibliográficos
Main Authors: Easwaran, Hariharan, Baylin, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586523/
https://ncbi.nlm.nih.gov/pubmed/22371454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0157
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