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Sex-specific signaling through Toll-Like Receptors 2 and 4 contributes to survival outcome of Coxsackievirus B3 infection in C57Bl/6 mice

BACKGROUND: Coxsackievirus B3 (CVB3) induces myocarditis, an inflammatory heart disease, which affects men more than women. Toll-like receptor (TLR) signaling has been shown to determine the severity of CVB3-induced myocarditis. No direct role for signaling through TLR2 had been shown in myocarditis...

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Bibliografiske detaljer
Main Authors: Roberts, Brian J, Dragon, Julie A, Moussawi, Mohamad, Huber, Sally A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586360/
https://ncbi.nlm.nih.gov/pubmed/23241283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2042-6410-3-25
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