The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity.

Previous studies have suggested that the two subunits of phosphatidylinositol (PI) 3-kinase, p85 and p110, function as localizing and catalytic subunits, respectively. Using recombinant p85 and p110 molecules, we have reconstituted the specific interaction between the two subunits of mouse PI 3-kina...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Klippel, A, Escobedo, J A, Hirano, M, Williams, L T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358634/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.4.2675-2685.1994
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