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Neuromyelitis Optica IgG Does Not Alter Aquaporin-4 Water Permeability, Plasma Membrane M1/M23 Isoform Content, or Supramolecular Assembly
Neuromyelitis optica (NMO) is thought to be caused by immunoglobulin G autoantibodies (NMO-IgG) against astrocyte water channel aquaporin-4 (AQP4). A recent study (Hinson et al. (2012) Proc Natl Acad Sci USA 109:1245- 1250) reported that NMO-IgG inhibits AQP4 water permeability directly and causes r...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586219/ https://ncbi.nlm.nih.gov/pubmed/22987455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22417 |
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