The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins.

PKR is a serine/threonine protein kinase induced by interferon treatment and activated by double-stranded RNAs. As a result of activation, PKR becomes autophosphorylated and catalyzes phosphorylation of the alpha subunit of protein synthesis eukaryotic initiation factor 2 (eIF-2). While studying the...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Lee, T G, Tang, N, Thompson, S, Miller, J, Katze, M G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7511204/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.4.2331
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