Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha.

Retinoids exert their physiological action by interacting with two families of nuclear receptors, the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs), which regulate gene expression by forming transcriptionally active heterodimeric RAR/RXR or homodimeric RXR/RXR complexes on DNA....

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Autors principals: Tate, B F, Allenby, G, Janocha, R, Kazmer, S, Speck, J, Sturzenbecker, L J, Abarzúa, P, Levin, A A, Grippo, J F
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC358599/
https://ncbi.nlm.nih.gov/pubmed/8139538
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