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The Novel Mas agonist, CGEN-856S, Attenuates Isoproterenol-Induced Cardiac Remodeling and Myocardial Infarction Injury in Rats

CGEN-856S is a novel Mas agonist. Herein, we examined the effects of this peptide on isoproterenol (ISO)-induced cardiac remodeling and myocardial infarction (MI) injury. We also sought to determine whether CGEN-856S activates the underlying mechanisms related to Mas receptor activation. Heart hyper...

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Autors principals: Savergnini, Sílvia Q., Ianzer, Danielle, Carvalho, Mariana B. L., Ferreira, Anderson J., Silva, Gerluza A. B., Marques, Fúlvia D., Peluso, Antônio Augusto B., Beiman, Merav, Cojocaru, Gady, Cohen, Yossi, Almeida, Alvair P., Rotman, Galit, Santos, Robson A. S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585977/
https://ncbi.nlm.nih.gov/pubmed/23469229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057757
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