Robustness and Backbone Motif of a Cancer Network Regulated by miR-17-92 Cluster during the G1/S Transition

Based on interactions among transcription factors, oncogenes, tumor suppressors and microRNAs, a Boolean model of cancer network regulated by miR-17-92 cluster is constructed, and the network is associated with the control of G1/S transition in the mammalian cell cycle. The robustness properties of...

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Detalhes bibliográficos
Main Authors: Yang, Lijian, Meng, Yan, Bao, Chun, Liu, Wangheng, Ma, Chengzhang, Li, Anbang, Xuan, Zhan, Shan, Ge, Jia, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585929/
https://ncbi.nlm.nih.gov/pubmed/23469179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057009
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